NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Prescription·Evidence index

Fenugreek and Testosterone: what the published research says

PubMed indexes 8 records that name Fenugreek and Testosterone together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Fenugreek and Testosterone. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

8 studies naming Fenugreek and Testosterone.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Efficacy of Furosap(TM), a novel Trigonella foenum-graecum seed extract, in Enhancing Testosterone Level and Improving Sperm Profile in Male Volunteers.

International journal of medical sciences · 2017 · PMID 28138310

Clinical Trial

“No significant changes were observed in serum lipid function, cholesterol, triglyceride, HDL and LDL levels, hemogram (CBC), hepatotoxicity and nephrotoxicity. Conclusion: Overall, the results demonstrate that FS, enriched in 20% protodioscin, is safe and effective in attenuating testosterone levels, healthy sperm profile, mental alertness, cardiovascular health and overall performance in human subjects.”

Maheshwari et al. · From the abstract

Names both Fenugreek and Testosterone in its title.

Testofen, a specialised Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males in a double-blind randomised clinical study.

The aging male : the official journal of the International Society for the Study of the Aging Male · 2016 · PMID 26791805

Randomized Controlled Trial

“Both total serum testosterone and free testosterone increased compared to placebo after 12 weeks of active treatment. Trigonella foenum-graecum seed extract is a safe and effective treatment for reducing symptoms of possible androgen deficiency, improves sexual function and increases serum testosterone in healthy middle-aged and older men.”

Rao et al. · From the abstract

Names both Fenugreek and Testosterone in its title.

Influence of a Specialized Trigonella foenum-graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study.

Phytotherapy research : PTR · 2015 · PMID 25914334

Randomized Controlled Trial

“The results indicate that this extract of T. foenum-graecum may be a useful treatment for increasing sexual arousal and desire in women.”

Rao et al. · From the abstract

Names both Fenugreek and Testosterone in its title.

Formulation, characterization, and efficacy evaluation of testolift: a novel testosterone-enhancing nutraceutical featuring synergistic black ginger methoxyflavones, fenugreek saponins, and zinc methionine via InSitu360 technology.

RSC advances · 2026 · PMID 42395749

“The InSitu360 technology enhanced the physicochemical and compositional stability of the formulation, supporting its robustness and suggesting potential for improved bioavailability, which warrants confirmation in future clinical studies. These results position Testolift as a promising natural testosterone-support formulation with potential applications in male health and muscle endurance.”

Amalraj et al. · From the abstract

Names both Fenugreek and Testosterone in its title.

Withania somnifera and Trigonella foenum-graecum as ingredients of testosterone-boosting supplements: Possible clinical implications.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 2025 · PMID 38628109

ReviewHuman subjects

“Withania somnifera may inhibit the effects of cortisol and prolactin on the hypothalamic-pituitary-gonadal axis and directly affect the hypothalamus. Trigonella foenum-graecum seeds contain the active substance diosgenin, which is a precursor for sex hormone synthesis in gonads.”

Skrzypiec-Spring et al. · From the abstract

Names both Fenugreek and Testosterone in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Fenugreek, Testosterone, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.