Interaction databaseSupplement × SupplementReviewed May 2026

Coenzyme Q10 and Garlic Extract, a synergy.

Aged garlic extract combined with coenzyme Q10 improved endothelial function and vascular elasticity in a randomized trial, with both agents contributing modest blood pressure lowering.

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

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What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances
Coenzyme Q10 and Garlic Extract
Pair type
Synergy
Evidence (highest tier)
Moderate
Source citations
1 source
Stack Score effect
+2 to your Stack Score (per scored synergy row).
Scope
Supplement × Supplement
Last verified
May 30, 2026

Synergy · Moderate evidence

Synergy

What is happening. Aged garlic extract combined with coenzyme Q10 improved endothelial function and vascular elasticity in a randomized trial, with both agents contributing modest blood pressure lowering.

Mechanism. Garlic enhances nitric oxide availability and reduces vascular oxidative stress, while coenzyme Q10 supports mitochondrial energy production and endothelial function, together improving vascular elasticity and modestly lowering blood pressure.

Recommendation. Can be combined for cardiovascular and blood pressure support. If on antihypertensive medication, monitor blood pressure for additive lowering.

Sources (1)
  1. Larijani VN et al. Beneficial effects of aged garlic extract and coenzyme Q10 on vascular elasticity and endothelial function: the FAITH randomized clinical trial. Nutrition. 2013;29(1):71-5. PMID 22858191

Stack Score

How this pair moves the number.

Effect on the composite score

If both Coenzyme Q10 and Garlic Extract are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

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