Interaction databaseSupplement × SupplementReviewed May 2026

Garlic Extract and Ginkgo Biloba, a caution.

Both are common in geriatric and cardiovascular use; combined antiplatelet effects are additive.

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

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What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances
Garlic Extract and Ginkgo Biloba
Pair type
Caution
Evidence (highest tier)
Moderate
Source citations
3 sources
Stack Score effect
−5 to your Stack Score (per scored caution row).
Scope
Supplement × Supplement
Last verified
May 30, 2026

Caution · Moderate evidence

Caution

What is happening. Both are common in geriatric and cardiovascular use; combined antiplatelet effects are additive.

Mechanism. Ginkgo inhibits PAF; allicin and ajoene in garlic impair platelet aggregation.

Recommendation. Use together only with surgical and bleeding-risk awareness. Discontinue both 1 to 2 weeks before scheduled procedures.

Sources (3)
  1. Bone KM. Potential interaction of Ginkgo biloba leaf with antiplatelet or anticoagulant drugs: what is the evidence? Mol Nutr Food Res. 2008;52(7):764-71. PMID 18214851
  2. Rahman K et al. Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans. J Nutr. 2000;130(11):2662-5. PMID 11053504
  3. Allison GL et al. Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms. J Nutr. 2006;136(3 Suppl):782S-788S. PMID 16484563

Stack Score

How this pair moves the number.

Effect on the composite score

If both Garlic Extract and Ginkgo Biloba are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

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