NutriStack
Fish Oil and Garlic Extract, a synergy.
Both lower LDL, blood pressure, and have mild antiplatelet effects; combined use is broadly cardio-supportive.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Fish Oil and Garlic Extract
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 3 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Both lower LDL, blood pressure, and have mild antiplatelet effects; combined use is broadly cardio-supportive.
Mechanism. Garlic raises HDL and lowers LDL via HMG-CoA reductase modulation; EPA/DHA lower triglycerides and reduce inflammatory eicosanoids.
Recommendation. Take together for additive cardiovascular benefit. Monitor for bleeding if combined with anticoagulants or NSAIDs.
Sources (3)
- Rahman K et al. Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans. J Nutr. 2000;130(11):2662-5. PMID 11053504
- Allison GL et al. Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms. J Nutr. 2006;136(3 Suppl):782S-788S. PMID 16484563
- Javaid M et al. Bleeding Risk in Patients Receiving Omega-3 Polyunsaturated Fatty Acids: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J Am Heart Assoc. 2024;13(10):e032390. PMID 38742535
Stack Score
How this pair moves the number.
Effect on the composite score
If both Fish Oil and Garlic Extract are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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