Supplement × Supplement·a caution·Emerging evidence

Anthocyanins (Bilberry Extract) + Fish Oil

Caution Emerging evidence

Both bilberry anthocyanins and high-dose fish oil can mildly reduce platelet aggregation. Taken together, and especially alongside anticoagulant or antiplatelet medication, they may have an additive effect on bleeding tendency.

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Pair type
Caution
Evidence
Emerging
Source citations
1
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionEmerging evidence

What is happening. Both bilberry anthocyanins and high-dose fish oil can mildly reduce platelet aggregation. Taken together, and especially alongside anticoagulant or antiplatelet medication, they may have an additive effect on bleeding tendency.

Mechanism. Omega-3 fatty acids reduce thromboxane-mediated platelet aggregation while anthocyanins have mild antiplatelet and endothelial effects, producing a potential additive antithrombotic effect.

Recommendation. Combining is generally fine for most people. Use caution at high doses, before surgery, or if on anticoagulants or antiplatelet drugs; discuss with a clinician in those situations and watch for easy bruising or prolonged bleeding.

Stack Score

How it moves the number.

Effect on the composite score

If both Anthocyanins (Bilberry Extract) and Fish Oil are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1
  • 1Krga I, Milenkovic D. Anthocyanins: from sources and bioavailability to cardiovascular-health benefits and molecular mechanisms of action. Journal of Agricultural and Food Chemistry. 2019.Needs sourceNo link

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