Fish Oil and Ginkgo Biloba, a caution.
Both have mild antiplatelet activity; combined chronic use can additively increase bleeding tendency, especially with concurrent NSAIDs or anticoagulants.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Fish Oil and Ginkgo Biloba
- Pair type
- Caution
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- −5 to your Stack Score (per scored caution row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Caution · Emerging evidence
Caution
What is happening. Both have mild antiplatelet activity; combined chronic use can additively increase bleeding tendency, especially with concurrent NSAIDs or anticoagulants.
Mechanism. Ginkgo inhibits platelet activating factor (PAF); fish oil EPA reduces thromboxane A2 production. Additive antiplatelet effect.
Recommendation. Use together cautiously. Stop both 7 to 14 days before scheduled surgery. Monitor for easy bruising, nosebleeds, or prolonged bleeding from cuts.
Sources (2)
- Bone KM. Potential interaction of Ginkgo biloba leaf with antiplatelet or anticoagulant drugs: what is the evidence? Mol Nutr Food Res. 2008;52(7):764-71. PMID 18214851
- Javaid M et al. Bleeding Risk in Patients Receiving Omega-3 Polyunsaturated Fatty Acids: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J Am Heart Assoc. 2024;13(10):e032390. PMID 38742535
Stack Score
How this pair moves the number.
Effect on the composite score
If both Fish Oil and Ginkgo Biloba are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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