Garlic Extract and Ginger Extract, a caution.
Combined antiplatelet activity may modestly increase bleeding tendency, particularly in those on anticoagulant or antiplatelet drugs or approaching surgery.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Garlic Extract and Ginger Extract
- Pair type
- Caution
- Evidence (highest tier)
- Emerging
- Source citations
- 3 sources
- Stack Score effect
- −5 to your Stack Score (per scored caution row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Caution · Emerging evidence
Caution
What is happening. Combined antiplatelet activity may modestly increase bleeding tendency, particularly in those on anticoagulant or antiplatelet drugs or approaching surgery.
Mechanism. Ginger inhibits thromboxane and platelet aggregation while garlic organosulfur compounds also suppress platelet aggregation, giving a potentially additive antiplatelet effect.
Recommendation. Generally well tolerated, but monitor for bruising or bleeding and stop both 1 to 2 weeks before surgery. Use caution with blood thinners.
Sources (3)
- Marx W et al. The Effect of Ginger (Zingiber officinale) on Platelet Aggregation: A Systematic Literature Review. PLoS One. 2015;10(10):e0141119. PMID 26488162
- Rahman K et al. Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans. J Nutr. 2000;130(11):2662-5. PMID 11053504
- Allison GL et al. Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms. J Nutr. 2006;136(3 Suppl):782S-788S. PMID 16484563
Stack Score
How this pair moves the number.
Effect on the composite score
If both Garlic Extract and Ginger Extract are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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