Interaction databaseSupplement × SupplementReviewed May 2026

Fish Oil and Ginger Extract, a caution.

Both reduce platelet aggregation, so the combination can additively increase bleeding tendency, especially with concurrent anticoagulants.

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

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Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances
Fish Oil and Ginger Extract
Pair type
Caution
Evidence (highest tier)
Emerging
Source citations
2 sources
Stack Score effect
−5 to your Stack Score (per scored caution row).
Scope
Supplement × Supplement
Last verified
May 30, 2026

Caution · Emerging evidence

Caution

What is happening. Both reduce platelet aggregation, so the combination can additively increase bleeding tendency, especially with concurrent anticoagulants.

Mechanism. Ginger gingerols inhibit thromboxane A2 mediated platelet aggregation while fish oil omega-3s shift eicosanoid production away from pro-aggregatory thromboxane A2, producing potentially additive antiplatelet effects.

Recommendation. Usually fine at typical doses, but monitor for easy bruising or bleeding and discontinue before surgery. Use caution if on blood thinners.

Sources (2)
  1. Marx W et al. The Effect of Ginger (Zingiber officinale) on Platelet Aggregation: A Systematic Literature Review. PLoS One. 2015;10(10):e0141119. PMID 26488162
  2. Javaid M et al. Bleeding Risk in Patients Receiving Omega-3 Polyunsaturated Fatty Acids: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. J Am Heart Assoc. 2024;13(10):e032390. PMID 38742535

Stack Score

How this pair moves the number.

Effect on the composite score

If both Fish Oil and Ginger Extract are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

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