What kind of interaction is it?

Caution: an interaction that may reduce efficacy or raise side-effect risk and warrants monitoring.

Is this interaction backed by published research?

Yes. NutriStack lists 1 citation row for the Felodipine + Garlic Extract pair, each linking to PubMed by PMID where available. Full sourcing methodology at https://nutristackapp.com/methodology/interactions.

Supplement × Prescription·a caution·Moderate evidence

Felodipine + Garlic Extract

Q: Can I take Felodipine and Garlic Extract together?

Possibly, but with caution. Felodipine and Garlic Extract have a documented caution-tier interaction. Garlic supplements have modest blood-pressure-lowering activity and can add to the antihypertensive effect of felodipine. The combined effect is usually small but may contribute to dizziness or symptomatic hypotension in sensitive individuals.

Q: How does this affect a NutriStack Stack Score?

-5 to your Stack Score per scored caution row.

Caution Moderate evidence

Garlic supplements have modest blood-pressure-lowering activity and can add to the antihypertensive effect of felodipine. The combined effect is usually small but may contribute to dizziness or symptomatic hypotension in sensitive individuals.

Supplement × Prescription

Open the interaction checker → Read the methodology

From the database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, and the recommendation.

Substances

Felodipine and Garlic Extract

Pair type

Caution

Evidence

Moderate

Source citations

Scope

Supplement × Prescription

Last verified

June 4, 2026

CautionModerate evidence

What is happening. Garlic supplements have modest blood-pressure-lowering activity and can add to the antihypertensive effect of felodipine. The combined effect is usually small but may contribute to dizziness or symptomatic hypotension in sensitive individuals.

Mechanism. Garlic-derived organosulfur compounds promote nitric-oxide-mediated vasodilation and mild blood-pressure reduction, adding to felodipine's vasodilatory antihypertensive effect.

Recommendation. Garlic supplements are generally acceptable with felodipine, but monitor blood pressure when starting or changing the dose and watch for lightheadedness, particularly in older adults or those on multiple antihypertensives.

Stack Score

How it moves the number.

Effect on the composite score

If both Felodipine and Garlic Extract are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1Ried K, Frank OR, Stocks NP, Fakler P, Sullivan T. Effect of garlic on blood pressure: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2008.Needs sourceNo link

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