What kind of interaction is it?

Caution: an interaction that may reduce efficacy or raise side-effect risk and warrants monitoring.

Is this interaction backed by published research?

Yes. NutriStack lists 1 citation row for the Fenofibrate + Garlic Extract pair, each linking to PubMed by PMID where available. Full sourcing methodology at https://nutristackapp.com/methodology/interactions.

Supplement × Prescription·a caution·Insufficient evidence

Fenofibrate + Garlic Extract

Q: Can I take Fenofibrate and Garlic Extract together?

Possibly, but with caution. Fenofibrate and Garlic Extract have a documented caution-tier interaction. Fenofibrate has antiplatelet-like effects and is reported to potentiate the action of anticoagulants. Concentrated garlic extract has mild antiplatelet activity, so combining the two could additively increase bleeding tendency, particularly in patients also taking warfarin, antiplatelet drugs, or other blood-thinning supplements.

Q: How does this affect a NutriStack Stack Score?

-5 to your Stack Score per scored caution row.

Caution Insufficient evidence

Fenofibrate has antiplatelet-like effects and is reported to potentiate the action of anticoagulants. Concentrated garlic extract has mild antiplatelet activity, so combining the two could additively increase bleeding tendency, particularly in patients also taking warfarin, antiplatelet drugs, or other blood-thinning supplements.

Supplement × Prescription

Open the interaction checker → Read the methodology

From the database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, and the recommendation.

Substances

Fenofibrate and Garlic Extract

Pair type

Caution

Evidence

Insufficient

Source citations

Scope

Supplement × Prescription

Last verified

June 4, 2026

CautionInsufficient evidence

What is happening. Fenofibrate has antiplatelet-like effects and is reported to potentiate the action of anticoagulants. Concentrated garlic extract has mild antiplatelet activity, so combining the two could additively increase bleeding tendency, particularly in patients also taking warfarin, antiplatelet drugs, or other blood-thinning supplements.

Mechanism. Garlic-derived organosulfur compounds inhibit platelet aggregation. Fenofibrate independently displays antiplatelet and anticoagulant-potentiating properties. Their effects on hemostasis can be additive, raising the theoretical risk of bleeding.

Recommendation. Use concentrated garlic supplements cautiously with fenofibrate, especially around surgery or alongside anticoagulant/antiplatelet therapy. Watch for easy bruising, nosebleeds, or prolonged bleeding, and inform clinicians of supplement use.

Stack Score

How it moves the number.

Effect on the composite score

If both Fenofibrate and Garlic Extract are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1Rahman K, Lowe GM. Garlic and cardiovascular disease: a critical review. J Nutr. 2006.Needs sourceNo link

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