Supplement × Supplement·a caution·Insufficient evidence

Ginkgo Biloba + Pueraria Mirifica

Caution Insufficient evidence

Ginkgo can increase bleeding tendency, and estrogenic botanicals can cause abnormal bleeding in susceptible users.

From the database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, and the recommendation.

Pair type
Caution
Evidence
Insufficient
Source citations
1
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionInsufficient evidence

What is happening. Ginkgo can increase bleeding tendency, and estrogenic botanicals can cause abnormal bleeding in susceptible users.

Mechanism. Potential additive bleeding concern and masking of estrogenic adverse effects.

Recommendation. Avoid high-dose combination before surgery or in unexplained bleeding; seek care for vaginal bleeding after menopause.

Stack Score

How it moves the number.

Effect on the composite score

If both Ginkgo Biloba and Pueraria Mirifica are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1
  • 1Manonai J et al. Pueraria mirifica clinical safety review. Journal of Ethnopharmacology. 2018.Needs sourceNo link

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