Supplement × Supplement·a caution·Insufficient evidence

IGF-1 LR3 (Long R3 IGF-1) + Potassium

Caution Insufficient evidence

Insulin-like signaling can shift potassium into cells during hypoglycemia treatment contexts, making electrolyte self-management unsafe.

From the database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, and the recommendation.

Pair type
Caution
Evidence
Insufficient
Source citations
1
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionInsufficient evidence

What is happening. Insulin-like signaling can shift potassium into cells during hypoglycemia treatment contexts, making electrolyte self-management unsafe.

Mechanism. Insulin/IGF-like metabolic signaling can affect cellular potassium shifts.

Recommendation. Do not self-correct symptoms with potassium; seek urgent care for severe weakness, palpitations, or hypoglycemia.

Stack Score

How it moves the number.

Effect on the composite score

If both IGF-1 LR3 (Long R3 IGF-1) and Potassium are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).

The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.

Sources

Sources, by evidence tier.

Every claim on this page is cited. PMIDs link straight to PubMed.

Reference material

1
  • 1WADA. 2026 Prohibited List. 2025.Needs sourceNo link

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