NutriStack
CautionEmerging evidence
What is happening. L-Theanine may add calming or sedating effects to lurasidone.
Mechanism. Potential additive CNS depression.
Recommendation. Use cautiously, especially during dose changes or if already sleepy.
Supplement × Prescription·a caution·Emerging evidence
L-Theanine + Lurasidone
Caution
Emerging evidence
L-Theanine may add calming or sedating effects to lurasidone.
From the database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Substances
L-Theanine and Lurasidone
Pair type
Caution
Evidence
Emerging
Source citations
1
Scope
Supplement × Prescription
Last verified
June 4, 2026
Stack Score
How it moves the number.
Effect on the composite score
If both L-Theanine and Lurasidone are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Sources
Sources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1U.S. National Library of Medicine. Lurasidone hydrochloride tablets US Prescribing Information. 2025.Needs sourceNo link
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