NutriStack
Maca Root and Tribulus Terrestris, a synergy.
Combining Tribulus and Maca pairs two libido and sexual function botanicals that act through largely separate pathways, giving complementary support for desire and erectile function.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Maca Root and Tribulus Terrestris
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Combining Tribulus and Maca pairs two libido and sexual function botanicals that act through largely separate pathways, giving complementary support for desire and erectile function.
Mechanism. Tribulus steroidal saponins (protodioscin) appear to act on nitric oxide and androgen-related signaling, while Maca works through non-hormonal central and adaptogenic pathways without raising testosterone, so the two address sexual function via different routes.
Recommendation. Reasonable to stack for libido or sexual function support. Use standard doses of each (Tribulus 250 to 750mg standardized for saponins, Maca 1.5 to 3g) and assess response over 8 to 12 weeks.
Sources (2)
- Gonzales GF. Ethnobiology and Ethnopharmacology of Lepidium meyenii (Maca), a Plant from the Peruvian Highlands. Evidence-Based Complementary and Alternative Medicine. 2012.
- Neychev V, Mitev V. Pro-sexual and androgen enhancing effects of Tribulus terrestris L.: Fact or Fiction. Journal of Ethnopharmacology. 2016.
Stack Score
How this pair moves the number.
Effect on the composite score
If both Maca Root and Tribulus Terrestris are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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