From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Prescription
Last verified
June 4, 2026
SynergyModerate evidence
What is happening. Magnesium can help correct tacrolimus-associated hypomagnesemia when monitored.
Mechanism. Supplementation replaces magnesium lost through renal wasting.
Recommendation. Use clinician-directed dosing and monitor magnesium and kidney function.
Stack Score
How it moves the number.
Effect on the composite score
If both Magnesium Glycinate and Tacrolimus are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1KDIGO. Kidney Transplant Recipient Guideline. American Journal of Transplantation. 2009.Needs sourceNo link