From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Prescription
Last verified
June 4, 2026
SynergyModerate evidence
What is happening. Low magnesium can increase torsades de pointes risk in patients taking QT-prolonging drugs such as ziprasidone.
Mechanism. Adequate magnesium supports cardiac repolarization stability and reduces arrhythmia vulnerability when QT is prolonged.
Recommendation. Correct magnesium deficiency under clinician guidance; do not use magnesium as a substitute for ECG or electrolyte monitoring in high-risk patients.
Stack Score
How it moves the number.
Effect on the composite score
If both Magnesium Glycinate and Ziprasidone are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Pfizer Inc. GEODON US Prescribing Information. 2024.Needs sourceNo link