Interaction databaseSupplement × SupplementReviewed May 2026

Tongkat Ali and Tribulus Terrestris, a synergy.

Tribulus and Tongkat Ali are both used to support libido and male sexual function, with complementary traditional and clinical use for that goal.

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

Sourcing standards·Evidence tiers

From the interaction database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances
Tongkat Ali and Tribulus Terrestris
Pair type
Synergy
Evidence (highest tier)
Emerging
Source citations
2 sources
Stack Score effect
+2 to your Stack Score (per scored synergy row).
Scope
Supplement × Supplement
Last verified
May 30, 2026

Synergy · Emerging evidence

Synergy

What is happening. Tribulus and Tongkat Ali are both used to support libido and male sexual function, with complementary traditional and clinical use for that goal.

Mechanism. Tribulus saponins act largely on libido and nitric oxide signaling while Tongkat Ali quassinoids may support free testosterone by reducing sex hormone binding globulin activity, giving complementary effects on sexual function.

Recommendation. Combination is reasonable for libido support. Monitor for overstimulation and discontinue if restlessness or sleep disturbance occurs.

Sources (2)
  1. Neychev V, Mitev V, Pro-sexual and androgen enhancing effects of Tribulus terrestris, Journal of Ethnopharmacology, 2016
  2. Talbott SM et al, Effect of Tongkat Ali on stress hormones and mood, Journal of the International Society of Sports Nutrition, 2013

Stack Score

How this pair moves the number.

Effect on the composite score

If both Tongkat Ali and Tribulus Terrestris are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

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