NutriStack
Symptom·Athletic·Reviewed May 30, 2026
Supplements for Delayed-onset muscle soreness (DOMS).
When delayed-onset muscle soreness (doms) is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01Fish OilModerate82% match
EPA and DHA dampen the inflammatory response to muscle microtrauma, which several trials link to reduced soreness and tenderness after eccentric exercise.
SuggestedHigh-EPA triglyceride fish oil - 02Curcumin PhytosomeModerate78% match
Curcumin lowers exercise-induced inflammatory signaling, with RCTs showing modestly reduced soreness and faster strength recovery after damaging workouts.
SuggestedPhytosome (phospholipid-bound) curcumin for absorption - 03Vitamin CLimited60% match
As an antioxidant it can buffer post-exercise oxidative stress that contributes to soreness when baseline intake is low.
SuggestedBuffered or standard ascorbic acid - 04L-CitrullineLimited55% match
Citrulline supports nitric oxide and ammonia clearance, and citrulline malate trials report lower perceived soreness in the days after resistance work.
SuggestedCitrulline malate, taken pre-workout - 05BCAAsLimited50% match
Branched-chain amino acids may slightly reduce muscle-damage markers and soreness, mainly in people with otherwise low protein intake.
Suggested2:1:1 BCAA powder around training
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These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.