NutriStack
Symptom·Athletic·Reviewed May 30, 2026
Supplements for Exercise leg cramps.
When exercise leg cramps is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01Magnesium GlycinateModerate78% match
Magnesium contributes to normal muscle relaxation and neuromuscular signaling, and correcting a deficiency may reduce cramp susceptibility in some people.
SuggestedMagnesium glycinate, 200 to 300 mg elemental in the evening - 02PotassiumLimited72% match
Potassium maintains the membrane potential needed for normal muscle contraction and relaxation, so sweat losses during exercise may contribute to cramping.
SuggestedPotassium-rich foods or potassium citrate with food - 03CalciumLimited62% match
Calcium is essential for the actin-myosin cross-bridge cycle that drives muscle contraction, so disrupted calcium balance can in theory influence cramping.
SuggestedCalcium citrate, 250 to 500 mg with meals - 04Vitamin D3Limited58% match
Vitamin D supports calcium handling and muscle function, and low status has been associated with muscle symptoms, though a direct cramp link is unproven.
SuggestedVitamin D3 softgels, 1000 to 2000 IU with a fatty meal - 05TaurineLimited55% match
Taurine helps regulate calcium handling and osmotic balance in muscle cells, which has been proposed to influence cramp threshold in athletes.
SuggestedTaurine powder, 1 to 2 g pre-exercise
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