Symptom·Inflammation·Reviewed June 4, 2026
Supplements for Systemic inflammation.
When systemic inflammation is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01HesperidinLimited55% match
Hesperetin downregulates NF-kB signaling and pro-inflammatory cytokines (CRP, IL-6, TNF-alpha) and scavenges reactive oxygen species, lowering markers of low-grade oxidative inflammation.
SuggestedHesperidin 500 mg daily, ideally micronized for absorption - 02TangeretinLimited50% match
Tangeretin suppresses NF-kB and MAPK signaling and downregulates pro-inflammatory mediators such as TNF-alpha, IL-6 and inducible nitric oxide synthase, while scavenging reactive oxygen species.
SuggestedCitrus polymethoxyflavone extract standardized to tangeretin, taken with food
Build your stack
Every match traces to a full profile.
These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.