From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyEmerging evidence
What is happening. Both may support insulin sensitivity and neuropathy-related metabolic pathways.
Mechanism. Complementary insulin-signaling and antioxidant mechanisms.
Recommendation. Monitor glucose and symptoms of shakiness or sweating if stacked.
Stack Score
How it moves the number.
Effect on the composite score
If both Alpha-Lipoic Acid and Cinnamon Extract are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Khan A et al. Cinnamon improves glucose and lipids. Diabetes Care. 2003.Needs sourceNo link