Supplement × Supplement·timing-sensitive·Emerging evidence
Berberine has antimicrobial activity that may reduce live probiotic viability if taken simultaneously.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
What is happening. Berberine has antimicrobial activity that may reduce live probiotic viability if taken simultaneously.
Mechanism. Antimicrobial effects during transit can impair probiotic survival.
Recommendation. Separate by at least 2-3 hours.
Space the doses apart by at least this window to avoid the conflict.
Effect on the composite score
If both Berberine and Bifidobacterium infantis 35624 are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Every claim on this page is cited. PMIDs link straight to PubMed.
Check your full routine
Drop your supplements and prescriptions into NutriStack and it runs every pair at once: every interaction, synergy, timing rule, and contraindication, each linked to its primary source.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.
NutriStack