NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Bifidobacterium infantis 35624 and Probiotics: what the published research says

PubMed indexes 8 records that name Bifidobacterium infantis 35624 and Probiotics together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

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An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Bifidobacterium infantis 35624 and Probiotics. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

8 studies naming Bifidobacterium infantis 35624 and Probiotics.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Efficacy of Bifidobacterium infantis 35624 in patients with irritable bowel syndrome: a meta-analysis.

Current medical research and opinion · 2017 · PMID 28166427

Meta-AnalysisSystematic ReviewHuman subjects

“Composite probiotics containing B. infantis might be an effective therapeutic option for IBS patients, which could significantly alleviate the symptoms of IBS without significant adverse effects. However, the efficacy of single probiotic B. infantis on IBS has not been confirmed yet, which needs to be further validated by more large-sized randomized clinical trials.”

Yuan et al. · Authors' conclusion

Names both Bifidobacterium infantis 35624 and Probiotics in its title.

Multi-Center, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Evaluate the Benefit of the Probiotic Bifidobacterium infantis 35624 in Non-Patients With Symptoms of Abdominal Discomfort and Bloating.

The American journal of gastroenterology · 2017 · PMID 27845337

Multicenter StudyRandomized Controlled Trial275 participants

“Unlike previous clinical studies in patients with IBS, B. infantis 35624 did not show a significant improvement in the mean severity of symptoms of abdominal discomfort and bloating in a non-patient population. This may be explained by the high placebo effect and the lower impact of functional bowel symptoms in the non-patient population.”

Ringel-Kulka et al. · Authors' conclusion

Names both Bifidobacterium infantis 35624 and Probiotics in its title.

Fecal excretion of Bifidobacterium infantis 35624 and changes in fecal microbiota after eight weeks of oral supplementation with encapsulated probiotic.

Gut microbes · 2013 · PMID 23549409

Randomized Controlled Trial

“Continuous probiotic administration was necessary to maintain steady-state transit. Given the complex spectrum of GI microbiota, however, monitoring perturbations in selected taxa may not be not a useful indicator of probiotic function.”

Charbonneau et al. · From the abstract

Names both Bifidobacterium infantis 35624 and Probiotics in its title.

Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells.

Gut · 2012 · PMID 22052061

Randomized Controlled Trial

“B. infantis administration to humans selectively promotes immunoregulatory responses, suggesting that this microbe may have therapeutic utility in patients with inflammatory disease. Cross-talk between multiple pattern-recognition receptors and metabolic pathways determines the innate and subsequent T regulatory cell response to B. infantis. These findings link nutrition, microbiota and the induction of tolerance within the gastrointestinal mucosa.”

Konieczna et al. · Authors' conclusion

Names both Bifidobacterium infantis 35624 and Probiotics in its title.

Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome.

The American journal of gastroenterology · 2006 · PMID 16863564

Multicenter StudyRandomized Controlled Trial

“B. infantis 35624 is a probiotic that specifically relieves many of the symptoms of IBS. At a dosage level of 1 x 10(8) cfu, it can be delivered by a capsule making it stable, convenient to administer, and amenable to widespread use. The lack of benefits observed with the other dosage levels of the probiotic highlight the need for clinical data in the final dosage form and dose of probiotic before these products should be used in practice.”

Whorwell et al. · Authors' conclusion

Names both Bifidobacterium infantis 35624 and Probiotics in its title.

Investigation of the changes in gut microbiota in high-fat-diet-induced obesity in rats with and without the probiotic supplementation Bifidobacterium infantis 35624.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2026 · PMID 41482882

“infantis 35624 supplementation caused changes in the gut microbiota. Beneficial strains associated with obesity may be clarified with species-specific studies to help prevent obesity.”

Ă–zdemir et al. · From the abstract

Names both Bifidobacterium infantis 35624 and Probiotics in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Bifidobacterium infantis 35624, Probiotics, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.