Bromelain and Ginkgo Biloba, a caution.
Bromelain has mild antiplatelet and fibrinolytic activity that can add to ginkgo's platelet-inhibiting effect, modestly increasing bleeding risk.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Bromelain and Ginkgo Biloba
- Pair type
- Caution
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- −5 to your Stack Score (per scored caution row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Caution · Emerging evidence
Caution
What is happening. Bromelain has mild antiplatelet and fibrinolytic activity that can add to ginkgo's platelet-inhibiting effect, modestly increasing bleeding risk.
Mechanism. Ginkgo inhibits platelet-activating factor and aggregation, while bromelain reduces platelet aggregation and promotes fibrinolysis by influencing plasminogen and fibrinogen, so the antiplatelet effects are additive.
Recommendation. Generally safe at normal doses, but use caution if combining with blood thinners or before surgery. Discontinue both ahead of dental or surgical procedures.
Sources (2)
Stack Score
How this pair moves the number.
Effect on the composite score
If both Bromelain and Ginkgo Biloba are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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