NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Caffeine and Rhodiola Rosea: what the published research says

PubMed indexes 5 records that name Caffeine and Rhodiola Rosea together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Caffeine and Rhodiola Rosea. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

5 studies naming Caffeine and Rhodiola Rosea.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Effects of Combined Caffeine and Rhodiola rosea Supplementation on Repeated Aerial Duel Performance and Neck Neuromuscular Function in Soccer Players.

Nutrients · 2026 · PMID 42123940

Randomized Controlled Trial

“These findings suggest that, in male collegiate soccer players, CAF and RHO may contribute differently to repeated aerial duel-related performance, and their combination may offer broader sport-specific benefits under repeated high-intensity demands.”

Dou et al. · Authors' conclusion

Names both Caffeine and Rhodiola Rosea in its title.

Effects of the Combined Supplementation of Caffeine and Rhodiola Rosea with Resistance Training on Lower Limb Explosive Power in Male Volleyball Players.

Nutrients · 2025 · PMID 40005009

Randomized Controlled Trial

“This study suggests that combining RHO and CAF optimizes high-intensity performance by enhancing explosive power, reducing fatigue, and improving recovery, presenting an effective nutritional strategy for volleyball athletes.”

Wang et al. · Authors' conclusion

Names both Caffeine and Rhodiola Rosea in its title.

Combined Effects of Rhodiola Rosea and Caffeine Supplementation on Straight Punch Explosive Power in Untrained and Trained Boxing Volunteers: A Synergistic Approach.

Metabolites · 2025 · PMID 40278391

“Combined supple mentation with CAF and RHO significantly enhances both explosive power and sustained output in boxing performance. This may result from improved energy metabolism efficiency and neuromuscular coordination, providing a promising nutritional strategy for high-intensity intermittent exercise.”

Tao et al. · Authors' conclusion

Names both Caffeine and Rhodiola Rosea in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Caffeine, Rhodiola Rosea, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.