NutriStack
CautionEmerging evidence
What is happening. Both can feel stimulating in some users and may increase anxiety or insomnia.
Mechanism. Additive central arousal and stress-response effects.
Recommendation. Start low and avoid late-day stacking.
Supplement × Supplement·a caution·Emerging evidence
Caffeine + Rhodiola Rosea
Caution
Emerging evidence
Both can feel stimulating in some users and may increase anxiety or insomnia.
From the database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Substances
Pair type
Caution
Evidence
Emerging
Source citations
1
Scope
Supplement × Supplement
Last verified
June 4, 2026
Stack Score
How it moves the number.
Effect on the composite score
If both Caffeine and Rhodiola Rosea are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
Sources
Sources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Guest NS et al. ISSN caffeine position stand. JISSN. 2021.Needs sourceNo link
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