What kind of interaction is it?

Caution: an interaction that may reduce efficacy or raise side-effect risk and warrants monitoring.

Is this interaction backed by published research?

Yes. NutriStack lists 2 citation rows for the Celecoxib + Ginkgo Biloba pair, each linking to PubMed by PMID where available. Full sourcing methodology at https://nutristackapp.com/methodology/interactions.

Interaction databaseSupplement × PrescriptionReviewed May 2026

Celecoxib and Ginkgo Biloba, a caution.

Q: Can I take Celecoxib and Ginkgo Biloba together?

Possibly, but with caution. Celecoxib and Ginkgo Biloba have a documented caution-tier interaction. Ginkgo biloba may add bleeding risk to celecoxib, particularly in people who also take aspirin or have ulcer history. Celecoxib is more GI-sparing than many NSAIDs, but it does not eliminate GI bleeding risk. Ginkgo has case reports of spontaneous bleeding and uncertain but plausible platelet effects.

Q: How does this affect a NutriStack Stack Score?

-5 to your Stack Score per scored caution row.

Ginkgo biloba may add bleeding risk to celecoxib, particularly in people who also take aspirin or have ulcer history. Celecoxib is more GI-sparing than many NSAIDs, but it does not eliminate GI bleeding risk. Ginkgo has case reports of spontaneous bleeding and uncertain but plausible platelet effects.

2 primary source citations. Emerging evidence. Last verified May 30, 2026.

Open the interaction checker →Read the methodology

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

Sourcing standards·Evidence tiers

From the interaction database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances: Celecoxib and Ginkgo Biloba
Pair type: Caution
Evidence (highest tier): Emerging
Source citations: 2 sources
Stack Score effect: −5 to your Stack Score (per scored caution row).
Scope: Supplement × Prescription
Last verified: May 30, 2026

Caution · Emerging evidence

Caution

What is happening. Ginkgo biloba may add bleeding risk to celecoxib, particularly in people who also take aspirin or have ulcer history. Celecoxib is more GI-sparing than many NSAIDs, but it does not eliminate GI bleeding risk. Ginkgo has case reports of spontaneous bleeding and uncertain but plausible platelet effects.

Mechanism. Ginkgo may reduce platelet activation through platelet-activating factor pathways. Celecoxib inhibits COX-2 and can still contribute to GI injury, especially when combined with aspirin or other risk factors.

Recommendation. Avoid ginkgo if you take celecoxib with aspirin or other bleeding-risk medicines. If used together, watch for unusual bruising, nosebleeds, black stools, or new severe headache.

Sources (2)

Stack Score

How this pair moves the number.

Effect on the composite score

If both Celecoxib and Ginkgo Biloba are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

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