Mechanism of the photo-induced activation of CoC bond in methylcobalamin-dependent methionine synthase.
Human subjects
Names both Combined Oral Contraceptive and Methylcobalamin in its title.
Supplement × Prescription·Evidence index
PubMed indexes 4 records that name Combined Oral Contraceptive and Methylcobalamin together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.
Every statement below is attributed to a named, dated, linked source.
This page lists published research relevant to Combined Oral Contraceptive and Methylcobalamin. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.
Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.
Names both Combined Oral Contraceptive and Methylcobalamin in its title.
“B3P86-D also performed well. A detailed analysis was undertaken to determine which atoms in cobalamin have large dispersion interactions with a methyl fragment of MeCbl.”
Names Combined Oral Contraceptive and Methylcobalamin together in an interaction, co-administration, or pharmacokinetic context.
“The analysis of thermodynamic and kinetic data provides a rationale as to why Co-C cleavage in reduced form requires prior departure of the axial base. Finally, the possible connection of present work to B12 enzymatic catalysis and the involvement of anion-radical-like [MeCbl]*- species in relevant methyl transfer reactions is discussed.”
Names Combined Oral Contraceptive and Methylcobalamin together in an interaction, co-administration, or pharmacokinetic context.
Names Combined Oral Contraceptive and Methylcobalamin together in an interaction, co-administration, or pharmacokinetic context.
Search-based evidence indexes have real limits, and it is worth being explicit about them:
NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Combined Oral Contraceptive, Methylcobalamin, and several hundred other substances.
The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.