What kind of interaction is it?

Synergy: a documented combination effect that is stronger or more useful than either substance taken alone.

Is this interaction backed by published research?

Yes. NutriStack lists 2 citation rows for the Enalapril + Garlic Extract pair, each linking to PubMed by PMID where available. Full sourcing methodology at https://nutristackapp.com/methodology/interactions.

Interaction databaseSupplement × PrescriptionReviewed May 2026

Enalapril and Garlic Extract, a synergy.

Q: Can I take Enalapril and Garlic Extract together?

Yes. The combination of Enalapril and Garlic Extract produces a measurable benefit. Garlic Extract lowers blood pressure modestly and has independent ACE-inhibitory activity in vitro. When combined with enalapril the effects are additive, which is helpful in uncontrolled hypertension but can produce mild hypotension if blood pressure is already at goal.

Q: How does this affect a NutriStack Stack Score?

+2 to your Stack Score per scored synergy row.

Garlic Extract lowers blood pressure modestly and has independent ACE-inhibitory activity in vitro. When combined with enalapril the effects are additive, which is helpful in uncontrolled hypertension but can produce mild hypotension if blood pressure is already at goal.

2 primary source citations. Moderate evidence. Last verified May 30, 2026.

Open the interaction checker →Read the methodology

One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.

Sourcing standards·Evidence tiers

From the interaction database

What the row says.

Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.

At a glance

Substances: Enalapril and Garlic Extract
Pair type: Synergy
Evidence (highest tier): Moderate
Source citations: 2 sources
Stack Score effect: +2 to your Stack Score (per scored synergy row).
Scope: Supplement × Prescription
Last verified: May 30, 2026

Synergy · Moderate evidence

Synergy

What is happening. Garlic Extract lowers blood pressure modestly and has independent ACE-inhibitory activity in vitro. When combined with enalapril the effects are additive, which is helpful in uncontrolled hypertension but can produce mild hypotension if blood pressure is already at goal.

Mechanism. Allicin and S-allylcysteine in garlic inhibit angiotensin-converting enzyme and promote endothelial nitric oxide production. These mechanisms add to those of enalapril.

Recommendation. If your blood pressure is already well controlled on enalapril, monitor at home before and after starting Garlic Extract. Typical aged garlic doses are 600-1200 mg/day. Tell your prescriber so your enalapril dose can be adjusted if needed.

Sources (2)

Stack Score

How this pair moves the number.

Effect on the composite score

If both Enalapril and Garlic Extract are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).

The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.

Check your full routine

One pair was the worked example. NutriStack runs every pair in your stack at once.

Drop in your supplements and prescriptions and the public database surfaces every interaction, synergy, timing rule, and contraindication, every one linked to its primary source.

Open the interaction checker →Browse the full research index