From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionInsufficient evidence
What is happening. Pygeum is usually well tolerated, but combining multiple supplements before urologic procedures can complicate bleeding and medication review.
Mechanism. Garlic has antiplatelet potential; perioperative bleeding risk assessment should include all supplements.
Recommendation. Stop nonessential supplements before procedures according to clinician instructions and disclose all products.
Stack Score
How it moves the number.
Effect on the composite score
If both Garlic Extract and Pygeum Africanum are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Melo EA et al. Pygeum and nettle BPH trial. Int Braz J Urol. 2005.Needs sourceNo link