From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
SynergyInsufficient evidence
What is happening. Zinc is often included in prostate formulas, but direct clinical synergy with pygeum is not established.
Mechanism. Nutritional prostate support plus botanical LUTS support.
Recommendation. Avoid chronic high-dose zinc and account for zinc from multivitamins.
Stack Score
How it moves the number.
Effect on the composite score
If both Pygeum Africanum and Zinc are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Wilt TJ et al. Phytotherapy for benign prostatic hyperplasia. Public Health Nutr. 2000.Needs sourceNo link