NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Pygeum Africanum and Saw Palmetto: what the published research says

PubMed indexes 3 records that name Pygeum Africanum and Saw Palmetto together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Pygeum Africanum and Saw Palmetto. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

3 studies naming Pygeum Africanum and Saw Palmetto.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

A scientific basis for the therapeutic effects of Pygeum africanum and Serenoa repens.

Urological research · 2000 · PMID 10929430

ReviewHuman subjects

“Thus, the clinical and biological activities of one preparation cannot be extrapolated to other preparations of the same plant source. Thus, studies described in this review which utilize the preparations that are manufactured by DEBAT (Pygeum africanum) or Pierre Fabre Medicament (Serenoa repens) are referred to by their trade names, Tadenan and Permixon, to differentiate them from other nonstandardized preparations of the same plants.”

Levin et al. · From the abstract

Names both Pygeum Africanum and Saw Palmetto in its title.

The efficacy of drugs for the treatment of LUTS/BPH, a study in 6 European countries.

European urology · 2007 · PMID 16846678

Multicenter StudyHuman subjects

“All drug treatments showed some improvement over watchful-waiting for most patients over the study period: the alpha-blockers were found to be the most effective. There were marked national differences in prescribing patterns, both in individual drug choice and in the use of combination therapies.”

Hutchison et al. · Authors' conclusion

Names Pygeum Africanum and Saw Palmetto together in an interaction, co-administration, or pharmacokinetic context.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Pygeum Africanum, Saw Palmetto, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.