NutriStack
Lycopene and Saw Palmetto, a synergy.
Lycopene and saw palmetto are frequently combined for prostate health, and combination trials suggest complementary benefit for benign prostatic symptoms.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
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At a glance
- Substances
- Lycopene and Saw Palmetto
- Pair type
- Synergy
- Evidence (highest tier)
- Moderate
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Moderate evidence
Synergy
What is happening. Lycopene and saw palmetto are frequently combined for prostate health, and combination trials suggest complementary benefit for benign prostatic symptoms.
Mechanism. Saw palmetto inhibits 5-alpha-reductase and exerts anti-inflammatory effects on prostatic tissue, while lycopene provides antioxidant and antiproliferative activity in the prostate, giving complementary mechanisms in benign prostatic hyperplasia.
Recommendation. Reasonable to combine for prostate and lower urinary tract support. Take with a meal to aid absorption of fat-soluble lycopene.
Sources (2)
- Morgia G et al. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus selenium and lycopene. Urologia Internationalis, 2010
- Schwarz S et al. Lycopene inhibits disease progression in patients with benign prostate hyperplasia. Journal of Nutrition, 2008
Stack Score
How this pair moves the number.
Effect on the composite score
If both Lycopene and Saw Palmetto are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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