The effect of MSM in the treatment of ankle arthrosis: Is MSM as effective as methylprednisolone or hyaluronic acid?
Comparative StudyAnimal study
Names both Hyaluronic Acid and MSM in its title.
Supplement × Supplement·Evidence index
PubMed indexes 7 records that name Hyaluronic Acid and MSM together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.
Every statement below is attributed to a named, dated, linked source.
This page lists published research relevant to Hyaluronic Acid and MSM. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.
Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.
Names both Hyaluronic Acid and MSM in its title.
Names both Hyaluronic Acid and MSM in its title.
Names both Hyaluronic Acid and MSM in its title.
Names both Hyaluronic Acid and MSM in its title.
“The combination of CS/GL/MSM/HA with collagen significantly outperforms collagen-free therapy in reducing pain, improving joint function, and decreasing symptomatic treatment needs in patients with knee OA exacerbations. These findings support the inclusion of collagen in OA combination therapy.”
Names Hyaluronic Acid and MSM together in an interaction, co-administration, or pharmacokinetic context.
“Results from this randomized, double blind, placebo-controlled community trial support the use of the Instaflex™ dietary supplement in alleviating joint pain severity in middle-aged and older adults, with mitigation of difficulty performing daily activities most apparent in subjects with knee pain.”
Names Hyaluronic Acid and MSM together in an interaction, co-administration, or pharmacokinetic context.
Names Hyaluronic Acid and MSM together in an interaction, co-administration, or pharmacokinetic context.
Search-based evidence indexes have real limits, and it is worth being explicit about them:
NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Hyaluronic Acid, MSM, and several hundred other substances.
The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.
NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.