From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Pair type
Timing Sensitive
Scope
Supplement × Prescription
Last verified
June 4, 2026
Timing SensitiveStrong evidence
What is happening. Iron supplements can chelate ibandronate and reduce absorption.
Mechanism. Multivalent cation binding prevents bisphosphonate absorption.
Recommendation. Take iron at a different time of day, not during the fasting ibandronate window.
TimingTiming & separation.
Space the doses apart by at least this window to avoid the conflict.
Stack Score
How it moves the number.
Effect on the composite score
If both Ibandronate and Iron are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1U.S. National Library of Medicine. Ibandronate Sodium Tablets US Prescribing Information. 2026.Needs sourceNo link