From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Pair type
Timing Sensitive
Scope
Supplement × Prescription
Last verified
June 4, 2026
Timing SensitiveStrong evidence
What is happening. Magnesium can bind oral ibandronate and reduce its already very low bioavailability.
Mechanism. Divalent cation chelation in the gastrointestinal tract.
Recommendation. Avoid magnesium before and for at least 60 minutes after ibandronate; later-day dosing is preferred.
TimingTiming & separation.
Space the doses apart by at least this window to avoid the conflict.
Stack Score
How it moves the number.
Effect on the composite score
If both Ibandronate and Magnesium Glycinate are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1U.S. National Library of Medicine. Ibandronate Sodium Tablets US Prescribing Information. 2026.Needs sourceNo link