From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Pair type
Timing Sensitive
Scope
Supplement × Prescription
Last verified
June 4, 2026
Timing SensitiveModerate evidence
What is happening. Zinc may bind oral ibandronate and reduce absorption if taken too close.
Mechanism. Cation chelation of bisphosphonate drug.
Recommendation. Separate zinc from ibandronate by at least 60 minutes, and ideally take zinc later with food.
TimingTiming & separation.
Space the doses apart by at least this window to avoid the conflict.
Stack Score
How it moves the number.
Effect on the composite score
If both Ibandronate and Zinc are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1U.S. National Library of Medicine. Ibandronate Sodium Tablets US Prescribing Information. 2026.Needs sourceNo link