NutriStack
Iodine and L-Tyrosine, a synergy.
Iodine and L-tyrosine are the two raw materials the thyroid combines to build thyroid hormone, so adequacy of both supports normal hormone synthesis.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Iodine and L-Tyrosine
- Pair type
- Synergy
- Evidence (highest tier)
- Strong
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Strong evidence
Synergy
What is happening. Iodine and L-tyrosine are the two raw materials the thyroid combines to build thyroid hormone, so adequacy of both supports normal hormone synthesis.
Mechanism. Tyrosyl residues on thyroglobulin are iodinated by thyroid peroxidase and then coupled to form T4 and T3, so both iodine and tyrosine are direct substrates of the same hormone-synthesis reaction.
Recommendation. Can be taken together for thyroid support. Avoid excess iodine, which can paradoxically impair thyroid function, and use cautiously if you have a thyroid disorder.
Sources (2)
- Zimmermann MB. Iodine deficiency. Endocrine Reviews. 2009
- Carvalho DP, Dupuy C. Thyroid hormone biosynthesis and release. Molecular and Cellular Endocrinology. 2017
Stack Score
How this pair moves the number.
Effect on the composite score
If both Iodine and L-Tyrosine are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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