From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Supplement
Last verified
June 4, 2026
CautionEmerging evidence
What is happening. Lactoferrin binds iron and may influence iron absorption or handling; extra iron is inappropriate in iron overload.
Mechanism. Iron binding and mucosal iron-handling effects.
Recommendation. Use ferritin, CBC, and transferrin saturation to guide iron supplementation.
Stack Score
How it moves the number.
Effect on the composite score
If both Iron and Lactoferrin are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Siqueiros-Cendon T et al. Lactoferrin iron-binding review. Int J Mol Sci. 2014.Needs sourceNo link