From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Prescription
Last verified
June 4, 2026
SynergyEmerging evidence
What is happening. Magnesium repletion can support normal airway and cardiac physiology when deficiency is present.
Mechanism. Magnesium can influence smooth muscle tone and arrhythmia vulnerability, while LABA therapy may stress cardiac rhythm in susceptible patients.
Recommendation. Use magnesium to correct documented or likely deficiency, not as a replacement for controller or rescue inhaler therapy.
Stack Score
How it moves the number.
Effect on the composite score
If both Magnesium Glycinate and Salmeterol/Fluticasone are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. 2025.Needs sourceNo link