NutriStack
Magnesium Glycinate and Zinc, timing-sensitive.
High-dose zinc and high-dose magnesium can compete at intestinal divalent cation transporters; effect is significant only at supplemental doses above typical RDA.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Magnesium Glycinate and Zinc
- Pair type
- Timing Sensitive
- Evidence (highest tier)
- Moderate
- Source citations
- 1 source
- Stack Score effect
- −5 to your Stack Score (per scored timing-sensitive row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Timing Sensitive · Moderate evidence
Timing Sensitive
What is happening. High-dose zinc and high-dose magnesium can compete at intestinal divalent cation transporters; effect is significant only at supplemental doses above typical RDA.
Mechanism. Both compete for absorption via DMT1 and other divalent cation transporters at high concentrations.
Recommendation. Take at separate meals, ideally 2 hours apart. Magnesium evening, zinc morning or midday is a common pattern.
Minimum separation. 2 hours
Sources (1)
- Spencer H et al. Effect of magnesium on the intestinal absorption of calcium in man. J Am Coll Nutr. 1994
Stack Score
How this pair moves the number.
Effect on the composite score
If both Magnesium Glycinate and Zinc are in the same stack, this pair applies −5 to your Stack Score (per scored timing-sensitive row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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