NutriStack
NAC and Spirulina, a synergy.
Spirulina and NAC both support antioxidant defenses through complementary mechanisms, with spirulina (phycocyanin) scavenging free radicals and NAC raising glutathione.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Pair type
- Synergy
- Evidence (highest tier)
- Emerging
- Source citations
- 2 sources
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Emerging evidence
Synergy
What is happening. Spirulina and NAC both support antioxidant defenses through complementary mechanisms, with spirulina (phycocyanin) scavenging free radicals and NAC raising glutathione.
Mechanism. NAC supplies cysteine to drive endogenous glutathione synthesis, while spirulina's phycocyanin directly scavenges reactive oxygen species and improves glutathione-related enzyme activity, reinforcing the same antioxidant network.
Recommendation. Reasonable to combine for antioxidant and detoxification support at standard doses. Effects are complementary rather than redundant.
Sources (2)
- Kepekci RA et al., Spirulina improves antioxidant status by reducing oxidative stress, Journal of Medicinal Food, 2010
- Atkuri KR et al., N-Acetylcysteine: a safe antidote for cysteine and glutathione deficiency, Current Opinion in Pharmacology, 2007
Stack Score
How this pair moves the number.
Effect on the composite score
If both NAC and Spirulina are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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