NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Spirulina and Vitamin C: what the published research says

PubMed indexes 3 records that name Spirulina and Vitamin C together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Spirulina and Vitamin C. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

3 studies naming Spirulina and Vitamin C.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

The hepatoprotective potential of Spirulina and vitamin C supplemention in cisplatin toxicity.

Food & function · 2012 · PMID 22119940

Animal study

“Light microscopy also showed that cisplatin treatment induced liver injury and that histopathological abnormalities were prevented by Spirulina and vitamin C supplementation. This protective effect was further substantiated by the estimation of antioxidant levels and extent of lipid peroxidation in the Spirulina, vitamin C and Spirulina + vitamin C supplemented groups as compared to cisplatin alone.”

Bhattacharyya et al. · From the abstract

Names both Spirulina and Vitamin C in its title.

In vitro evaluation of protective effects of ascorbic acid and water extract of Spirulina plantesis (blue green algae) on 5-fluorouracil-induced lipid peroxidation.

Acta poloniae pharmaceutica · 2007 · PMID 18536159

Animal study

“This evaluation was done by measuring the malondialdehyde (MDA), reduced glutathione (GSH), 4-hydroxy-2-nonenal (4-HNE) and nitric oxide (NO) content of the tissue as markers of lipid peroxidation. The results suggest that ascorbic acid and water extract of Spirulina plantesis could suppress the 5-FU-induced lipid peroxidation to a significant extent.”

Ray et al. · From the abstract

Names both Spirulina and Vitamin C in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Spirulina, Vitamin C, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.