From the databaseWhat the row says.
Every entry follows the same shape: what is happening, the mechanism, and the recommendation.
Scope
Supplement × Prescription
Last verified
June 4, 2026
CautionModerate evidence
What is happening. Antimuscarinic slowing of gastrointestinal transit may increase mucosal injury risk from solid oral potassium products.
Mechanism. Reduced gastrointestinal motility increases contact time between potassium salts and mucosa.
Recommendation. Use potassium only under clinician guidance; consider non-solid formulations if potassium is necessary and constipation or dysphagia is present.
Stack Score
How it moves the number.
Effect on the composite score
If both Potassium and Solifenacin are in the same stack, this pair applies −5 to your Stack Score (per scored caution row).
The full algorithm, the clamping rules, and four worked stacks are at /methodology/stack-score.
SourcesSources, by evidence tier.
Every claim on this page is cited. PMIDs link straight to PubMed.
Reference material
1- 1U.S. National Library of Medicine. Solifenacin Succinate Tablets US Prescribing Information. 2026.Needs sourceNo link