NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Silicon and Vitamin B7: what the published research says

PubMed indexes 8 records that name Silicon and Vitamin B7 together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Silicon and Vitamin B7. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

8 studies naming Silicon and Vitamin B7.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

Cancer-Targeted Chitosan-Biotin-Conjugated Mesoporous Silica Nanoparticles as Carriers of Zinc Complexes to Achieve Enhanced Chemotherapy In Vitro and In Vivo.

ACS applied bio materials · 2022 · PMID 35014809

Human subjects

“Moreover, a lower range of LD50 values (153.6-335.5 μM) were observed upon treatment zebrafish embryos with NPs in vivo. Because of the anatomical similarity to the human heart, the heart rate of NP-treated zebrafish has been analyzed in assessing the cardiac functions, which is in favor of the early clinical trials of ZnMBC (1/2)@MSNs-CTS-biotin candidates for their further evaluation as a chemotherapeutic and chemopreventive agent toward human cancers, especially…”

Kundu et al. · From the abstract

Names both Silicon and Vitamin B7 in its title.

Conjugate of biotin with silicon(IV) phthalocyanine for tumor-targeting photodynamic therapy.

Journal of photochemistry and photobiology. B, Biology · 2017 · PMID 28802175

Human subjects

“Furthermore, the dark toxicity of SiPc-biotin toward human normal liver cell lines LO2 was much lower than that of its precursor SiPc-pip. The targeting photodynamic activity and low dark toxicity suggest that SiPc-biotin is a promising photosensitizer for tumor-targeting photodynamic therapy.”

Li et al. · From the abstract

Names both Silicon and Vitamin B7 in its title.

Biotin-decorated fluorescent silica nanoparticles with aggregation-induced emission characteristics: fabrication, cytotoxicity and biological applications.

Journal of materials chemistry. B · 2013 · PMID 32260772

“The FSNPs worked as fluorescent visualizers for selective imaging of the cytoplasm of tumor cells with over-expressed biotin receptors. The fluorescent nanoparticles were lastingly retained inside the living cells, thus enabling long-term tumor cell tracking over multiple passages and quantitative analysis of tumor cell migration.”

Li et al. · From the abstract

Names both Silicon and Vitamin B7 in its title.

On the adsorption behavior of biotin-binding proteins on gold and silica.

Langmuir : the ACS journal of surfaces and colloids · 2010 · PMID 19736978

“Furthermore, we report that SAv resists adsorption to silica over a wide range of pH and ionic strength. The contrast in the binding behavior of SAv on silica and on gold suggests a simple strategy for the selective biofunctionalization of nano- or microstructured surfaces.”

Wolny et al. · From the abstract

Names both Silicon and Vitamin B7 in its title.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Silicon, Vitamin B7, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.