NutriStack
Chromium and Vitamin B7, a synergy.
Chromium picolinate combined with biotin (vitamin B7) has improved fasting glucose and glycemic markers more than chromium alone in studies of impaired glucose control.
One pair, every claim cited. The two substances, the type, the mechanism, the recommendation, and the primary literature.
Same shape as the other 1,729 pairs in the public database.
From the interaction database
What the row says.
Every entry follows the same shape: what is happening, the mechanism, the recommendation, and the primary literature.
At a glance
- Substances
- Chromium and Vitamin B7
- Pair type
- Synergy
- Evidence (highest tier)
- Moderate
- Source citations
- 1 source
- Stack Score effect
- +2 to your Stack Score (per scored synergy row).
- Scope
- Supplement × Supplement
- Last verified
- May 30, 2026
Synergy · Moderate evidence
Synergy
What is happening. Chromium picolinate combined with biotin (vitamin B7) has improved fasting glucose and glycemic markers more than chromium alone in studies of impaired glucose control.
Mechanism. Chromium enhances insulin receptor sensitivity, while biotin is a cofactor for carboxylase enzymes (including pyruvate carboxylase and acetyl-CoA carboxylase) and upregulates glucokinase, giving complementary effects on glucose handling.
Recommendation. The two are commonly paired and can be taken together for glycemic support. Not a substitute for prescribed diabetes therapy.
Stack Score
How this pair moves the number.
Effect on the composite score
If both Chromium and Vitamin B7 are in the same stack, this pair applies +2 to your Stack Score (per scored synergy row).
The full algorithm, the clamping rules, and four worked stacks are documented at /methodology/stack-score.
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