NSTK · 01.2026Independent supplement reference
NutriStack
Edition 1.0Updated August 1, 2026

Supplement × Supplement·Evidence index

Chromium and Inositol: what the published research says

PubMed indexes 4 records that name Chromium and Inositol together, either in the title or in an interaction, co-administration, or pharmacokinetic context. Each one is listed below with its study design and, where the abstract states one, the authors’ own conclusion, quoted and linked. This page reports that literature. It does not tell you whether to combine them.

Read this first

An evidence index, not guidance.

Every statement below is attributed to a named, dated, linked source.

This page lists published research relevant to Chromium and Inositol. It deliberately does not state whether the combination is safe, whether it interacts, in which direction, at what dose, or how far apart to take them.

The research

4 studies naming Chromium and Inositol.

Strongest relevance first: papers naming both substances in the title, then human trials and systematic reviews.

An Evaluation of a Nutraceutical with Berberine, Curcumin, Inositol, Banaba and Chromium Picolinate in Patients with Fasting Dysglycemia.

Diabetes, metabolic syndrome and obesity : targets and therapy · 2020 · PMID 32184644

“A nutraceutical containing Berberine, Curcumin, Inositol, Banaba, and Chromium Picolinate can be helpful in improving glyco-metabolic compensation, TC and Tg value, and in reducing inflammatory status in patients with dysglycemia.”

Derosa et al. · Authors' conclusion

Names both Chromium and Inositol in its title.

Nutrient-based therapies for bipolar disorder: a systematic review.

Psychotherapy and psychosomatics · 2013 · PMID 23147067

Systematic ReviewHuman subjects

“Given the potential public health impact of identifying adjunct treatments that improve psychiatric as well as physical health outcomes, nutritional treatments appear promising for the management of bipolar disorder but require further study.”

Sylvia et al. · Authors' conclusion

Names Chromium and Inositol together in an interaction, co-administration, or pharmacokinetic context.

The Effectiveness and Safety of a Nutraceutical Combination in Overweight Patients with Metabolic Syndrome.

Nutrients · 2024 · PMID 39683371

Observational StudyHuman subjects

“Thus, on the basis of these data, it may be stated that the specific nutraceutical combination used in the present study significantly ameliorated a number of metabolic parameters without measurable side effects. The efficacy and safety of the product were, therefore, confirmed in our group of patients.”

Ricottini et al. · Authors' conclusion

Names Chromium and Inositol together in an interaction, co-administration, or pharmacokinetic context.

Efficacy of combination therapy of inositols, antioxidants and vitamins in obese and non-obese women with polycystic ovary syndrome: an observational study.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology · 2020 · PMID 31339394

Observational StudyHuman subjects

“Combined use of insulin sensitising agents (myo-inositol, D-chiro-inositol and chromium picolinate), antioxidants (N-acetylcysteine and lycopene), and vitamins (vitamin D, biotin and folic acid) is safe and effective in obese and non-obese women with PCOS.What are the implications of these findings for clinical practice and/or further research?”

Advani et al. · From the abstract

Names Chromium and Inositol together in an interaction, co-administration, or pharmacokinetic context.

Limitations

What this evidence cannot tell you.

Search-based evidence indexes have real limits, and it is worth being explicit about them:

NutriStack

Track what you actually take.

NutriStack is a free iPhone app for organising a supplement routine: what you take, when, and what the published record says about it. Its exploratory interaction checker covers Chromium, Inositol, and several hundred other substances.

The checker is a research and organisation tool, not a clinical decision aid, and its per-pair assessments are excluded from search until they pass claim-level review.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.