Symptom·Neurologic·Reviewed May 30, 2026

Supplements for Chemotherapy-induced peripheral neuropathy (adjunctive support).

When chemotherapy-induced peripheral neuropathy (adjunctive support) is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.

Supplements

Ranked by relevance, top first.

Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.

  1. 01
    Vitamin B6Limited
    62% match

    Pyridoxine supports peripheral nerve metabolism and is sometimes used adjunctively, though balance matters since excess B6 is itself neurotoxic.

    SuggestedVitamin B6 (pyridoxal-5-phosphate) at low dose, no more than about 50 mg daily
  2. 02
    60% match

    Its antioxidant action targets the oxidative nerve injury thought to drive platinum and taxane induced neuropathy.

    SuggestedAlpha-Lipoic Acid 600 mg daily
  3. 03
    45% match

    Supports mitochondrial function and nerve repair, with some early interest in taxane neuropathy.

    SuggestedAcetyl-L-Carnitine 500 to 1000 mg daily
  4. 04
    Fish OilLimited
    42% match

    Omega-3 anti-inflammatory and neuroprotective effects have shown a possible protective signal in small paclitaxel neuropathy studies.

    SuggestedFish Oil providing about 1 to 2 g EPA/DHA daily
  5. 05
    40% match

    Maintaining magnesium status supports normal nerve excitability and may ease cramping that accompanies neuropathy.

    SuggestedMagnesium Glycinate 200 to 400 mg elemental daily
  6. 06
    38% match

    Active B12 supports myelin and nerve maintenance and corrects a deficiency that can compound chemotherapy nerve damage.

    SuggestedMethylcobalamin 1000 mcg daily

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These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.