Symptom·Neurologic·Reviewed May 30, 2026
Supplements for Chemotherapy-induced peripheral neuropathy (adjunctive support).
When chemotherapy-induced peripheral neuropathy (adjunctive support) is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01Vitamin B6Limited62% match
Pyridoxine supports peripheral nerve metabolism and is sometimes used adjunctively, though balance matters since excess B6 is itself neurotoxic.
SuggestedVitamin B6 (pyridoxal-5-phosphate) at low dose, no more than about 50 mg daily - 02Alpha-Lipoic AcidLimited60% match
Its antioxidant action targets the oxidative nerve injury thought to drive platinum and taxane induced neuropathy.
SuggestedAlpha-Lipoic Acid 600 mg daily - 03Acetyl-L-CarnitineLimited45% match
Supports mitochondrial function and nerve repair, with some early interest in taxane neuropathy.
SuggestedAcetyl-L-Carnitine 500 to 1000 mg daily - 04Fish OilLimited42% match
Omega-3 anti-inflammatory and neuroprotective effects have shown a possible protective signal in small paclitaxel neuropathy studies.
SuggestedFish Oil providing about 1 to 2 g EPA/DHA daily - 05Magnesium GlycinateLimited40% match
Maintaining magnesium status supports normal nerve excitability and may ease cramping that accompanies neuropathy.
SuggestedMagnesium Glycinate 200 to 400 mg elemental daily - 06MethylcobalaminLimited38% match
Active B12 supports myelin and nerve maintenance and corrects a deficiency that can compound chemotherapy nerve damage.
SuggestedMethylcobalamin 1000 mcg daily
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These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.