NutriStack
Symptom·Pain·Reviewed May 30, 2026
Supplements for Fibromyalgia support.
When fibromyalgia support is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01Magnesium GlycinateLimited78% match
Magnesium modulates NMDA receptor activity and muscle relaxation, and the gentle glycinate form may help with pain sensitivity and sleep, mainly when intake is low.
SuggestedMagnesium glycinate capsule providing 200 to 400 mg elemental magnesium in the evening - 02Vitamin D3Moderate72% match
Vitamin D supports muscle and nerve function, and correcting low vitamin D may reduce musculoskeletal pain in deficient individuals.
SuggestedVitamin D3 softgel, 1000 to 2000 IU daily, dosed to lab levels - 03Coenzyme Q10Limited70% match
CoQ10 supports mitochondrial energy and has antioxidant effects, and small trials report reduced pain and fatigue in fibromyalgia.
SuggestedUbiquinol softgel, 100 to 300 mg daily with food - 04SAMeLimited64% match
SAMe is a methyl donor involved in neurotransmitter and joint metabolism, and some older trials suggest it may ease pain and mood symptoms in fibromyalgia.
SuggestedEnteric-coated SAMe tablet, 400 to 800 mg daily on an empty stomach - 05Acetyl-L-CarnitineLimited60% match
Acetyl-L-Carnitine supports mitochondrial energy and nerve function, and limited trials report some improvement in pain and mood in fibromyalgia.
SuggestedAcetyl-L-Carnitine capsule, 500 mg twice daily - 065-HTPLimited57% match
5-HTP is a serotonin precursor, and because low serotonergic tone is linked to pain and sleep disturbance it may modestly support fibromyalgia symptoms.
Suggested5-HTP capsule, 50 to 100 mg in the evening
Build your stack
Every match traces to a full profile.
These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.