Symptom·Pain·Reviewed May 30, 2026

Supplements for Lower back pain.

When lower back pain is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.

Supplements

Ranked by relevance, top first.

Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.

  1. 01
    76% match

    Curcumin inhibits inflammatory signaling (NF-kB, COX-2), which may reduce pain in inflammatory and osteoarthritic back conditions.

    SuggestedCurcumin phytosome (Meriva)
  2. 02
    BoswelliaModerate
    70% match

    Boswellic acids inhibit 5-lipoxygenase and leukotriene synthesis, with moderate evidence for reducing joint and spinal inflammatory pain.

    SuggestedBoswellia serrata standardized to AKBA
  3. 03
    Vitamin D3Limited
    64% match

    Vitamin D supports musculoskeletal and bone health, and deficiency is associated with greater chronic low back pain in observational studies.

    SuggestedVitamin D3 (cholecalciferol)
  4. 04
    62% match

    Magnesium supports muscle relaxation and NMDA-receptor modulation, which may relieve muscular contributions to and central sensitization of chronic back pain.

    SuggestedMagnesium glycinate
  5. 05
    Fish OilLimited
    58% match

    Omega-3 fatty acids shift eicosanoid balance toward anti-inflammatory mediators, which may modestly reduce musculoskeletal pain.

    SuggestedHigh-EPA fish oil
  6. 06
    MSMLimited
    55% match

    MSM is a sulfur donor with antioxidant and mild anti-inflammatory activity that may reduce joint pain, with limited spine-specific data.

    SuggestedMethylsulfonylmethane (OptiMSM)

Build your stack

Every match traces to a full profile.

These rankings come from the same library that powers the NutriStack app. Open any supplement for full dosing, forms, interactions, and citations.

NutriStack is an informational and organizational tool, not a medical service, and not a substitute for professional advice. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or medication.