Symptom·Neurologic·Reviewed May 30, 2026
Supplements for Nicotine / smoking cessation support.
When nicotine / smoking cessation support is the complaint, these are the supplements most often associated with it in the NutriStack library, ranked by how directly each one targets it and by the strength of the evidence.
Ranked by relevance, top first.
Relevance reflects how directly each supplement targets this symptom in the NutriStack map. Evidence is the supplement’s own rating. Open any name for the full profile.
- 01NACLimited78% match
NAC may modulate glutamate signaling in reward pathways, and small trials suggest it could reduce craving and the reinforcing value of nicotine, though results are mixed.
SuggestedN-acetylcysteine capsules, 1200 to 2400 mg per day in divided doses - 02L-TheanineLimited66% match
L-theanine may promote alpha brain wave activity and could blunt the anxiety and irritability that often trigger relapse during early withdrawal, though direct cessation data are lacking.
SuggestedL-theanine capsules, 100 to 200 mg as needed during cravings - 03L-TyrosineLimited62% match
As a dopamine precursor, L-tyrosine may help replenish catecholamines and theoretically ease the low mood and poor focus that follow nicotine withdrawal, but direct cessation evidence is essentially absent.
SuggestedFree-form L-tyrosine, 500 to 1000 mg on an empty stomach in the morning - 04AshwagandhaLimited60% match
Ashwagandha may lower cortisol and perceived stress, which could indirectly help with the elevated stress load common when quitting nicotine, though it has no direct cessation evidence.
SuggestedStandardized root extract (KSM-66 or Sensoril), 300 to 600 mg per day - 05Magnesium GlycinateLimited57% match
Magnesium supports GABAergic tone and may modestly ease the irritability, muscle tension, and disrupted sleep that can accompany withdrawal, though data specific to cessation are sparse.
SuggestedMagnesium glycinate, 200 to 400 mg elemental in the evening - 06Vitamin CLimited55% match
Smoking depletes plasma ascorbate, so vitamin C helps restore antioxidant status, but it is not shown to aid quitting itself.
SuggestedVitamin C (ascorbic acid), 500 mg per day with food
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